Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dlg4bDiscs, large homolog 4b (Drosophila); Belongs to the MAGUK family. (453 aa)    
Predicted Functional Partners:
grin1a
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
    
 0.849
or132-5
Odorant receptor, family H, subfamily 132, member 5.
    
 0.783
llgl2
LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family.
   
 0.765
grin1b
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
    
 0.741
grin2aa
Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a.
    
 0.735
or104-2
Olfactory receptor.
    
 0.722
grin3a
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A.
    
 0.697
or115-15
Odorant receptor, family F, subfamily 115, member 15.
    
 0.688
gps2
G protein pathway suppressor 2.
      
 0.688
cdk5
Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.
    
  0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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