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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phf23aPHD finger protein 23A; Acts as a negative regulator of autophagy. (296 aa)    
Predicted Functional Partners:
kansl2
KAT8 regulatory NSL complex subunit 2.
   
 
 0.871
cutc
CutC copper transporter homolog (E. coli).
      
 0.744
nup98
Nucleoporin 98.
   
 
 0.706
mcrs1
Microspherule protein 1.
   
 
 0.703
kansl3
KAT8 regulatory NSL complex subunit 3; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
    
 
 0.668
SHC3
SHC adaptor protein 3.
      
 0.585
kat7b
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
   
 
 0.583
kat6b
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 
 0.581
taf3
TAF3 RNA polymerase II, TATA box-binding protein (TBP)-associated facto.
      
 0.559
bptf
Bromodomain PHD finger transcription factor.
   
 
 0.559
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.