Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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sepsecsO-phosphoseryl-tRNA(Sec) selenium transferase; Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl- tRNA(Sec) required for selenoprotein biosynthesis. Belongs to the SepSecS family. (490 aa)    
Predicted Functional Partners:
sephs2
Selenophosphate synthetase 2.
     
 0.996
PSTK
Uncharacterized protein.
     
 0.996
LOC101884223
Uncharacterized protein.
     
 0.986
trnau1apb
tRNA selenocysteine 1-associated protein 1-like; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Belongs to the RRM TRSPAP family.
      
 0.973
sephs1
Selenide, water dikinase 1; Synthesizes selenophosphate from selenide and ATP.
     
 0.961
sars1
Serine--tRNA ligase, cytoplasmic; Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the vegfa core promoter and prevents myc binding and transcriptional activation by myc. Thereby inhibits the production of vegfa and sprouting angiogenesis mediated by vegfa. Belongs t [...]
     
 0.931
sars2
Seryl-tRNA synthetase 2, mitochondrial.
     
 0.912
eefsec
Eukaryotic elongation factor, selenocysteine-tRNA-specific.
      
 0.864
secisbp2
SECIS-binding protein 2.
      
 0.856
tsen2
TSEN2 tRNA-splicing endonuclease subunit.
      
 0.834
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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