Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
atrnl1bAttractin-like 1b. (1364 aa)    
Predicted Functional Partners:
mgrn1b
Mahogunin, ring finger 1b.
   
 
 0.791
smo
Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.700
kcnc2
Potassium voltage-gated channel, Shaw-related subfamily, member 2; Belongs to the potassium channel family.
   
  
 0.681
mgrn1a
Probable E3 ubiquitin-protein ligase MGRN1; E3 ubiquitin-protein ligase. Acts also as a negative regulator of hedgehog signaling.
   
 
 0.647
phactr1
Phosphatase and actin regulator.
   
  
 0.611
RNF157
Si:dkey-49c17.3.
   
 
 0.588
ankrd46b
Ankyrin repeat domain-containing protein 46.
    
   0.561
rims1b
Regulating synaptic membrane exocytosis 1b.
      
 0.561
cacna2d3
Calcium channel, voltage-dependent, alpha2/delta subunit 3.
      
 0.560
pla2g4aa
Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response.
     
  0.559
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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