node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cdh17 | cdh18a | ENSDARP00000042894 | ENSDARP00000089931 | Cadherin 17, LI cadherin (liver-intestine). | Cadherin 18, type 2a. | 0.666 |
cdh17 | ctnnb1 | ENSDARP00000042894 | ENSDARP00000139205 | Cadherin 17, LI cadherin (liver-intestine). | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.742 |
cdh17 | ctnnb2 | ENSDARP00000042894 | ENSDARP00000076115 | Cadherin 17, LI cadherin (liver-intestine). | Catenin, beta 2. | 0.705 |
cdh17 | jupa | ENSDARP00000042894 | ENSDARP00000026915 | Cadherin 17, LI cadherin (liver-intestine). | Junction plakoglobin a. | 0.672 |
cdh17 | jupb | ENSDARP00000042894 | ENSDARP00000076517 | Cadherin 17, LI cadherin (liver-intestine). | Junction plakoglobin b. | 0.663 |
cdh17 | pax2a | ENSDARP00000042894 | ENSDARP00000071466 | Cadherin 17, LI cadherin (liver-intestine). | Paired box protein Pax-2a; Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. | 0.679 |
cdh17 | slc12a1 | ENSDARP00000042894 | ENSDARP00000140839 | Cadherin 17, LI cadherin (liver-intestine). | Solute carrier family 12 member 1. | 0.764 |
cdh17 | slc12a3 | ENSDARP00000042894 | ENSDARP00000025500 | Cadherin 17, LI cadherin (liver-intestine). | Solute carrier family 12 member 3. | 0.773 |
cdh17 | slc20a1a | ENSDARP00000042894 | ENSDARP00000005218 | Cadherin 17, LI cadherin (liver-intestine). | Sodium-dependent phosphate transporter 1-A; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport; Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. | 0.837 |
cdh17 | wt1b | ENSDARP00000042894 | ENSDARP00000121364 | Cadherin 17, LI cadherin (liver-intestine). | WT1 transcription factor b. | 0.807 |
cdh18a | cdh17 | ENSDARP00000089931 | ENSDARP00000042894 | Cadherin 18, type 2a. | Cadherin 17, LI cadherin (liver-intestine). | 0.666 |
cdh18a | ctnnb1 | ENSDARP00000089931 | ENSDARP00000139205 | Cadherin 18, type 2a. | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | 0.643 |
cdh18a | ctnnb2 | ENSDARP00000089931 | ENSDARP00000076115 | Cadherin 18, type 2a. | Catenin, beta 2. | 0.643 |
cdh18a | jupa | ENSDARP00000089931 | ENSDARP00000026915 | Cadherin 18, type 2a. | Junction plakoglobin a. | 0.626 |
cdh18a | jupb | ENSDARP00000089931 | ENSDARP00000076517 | Cadherin 18, type 2a. | Junction plakoglobin b. | 0.626 |
ctnnb1 | cdh17 | ENSDARP00000139205 | ENSDARP00000042894 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Cadherin 17, LI cadherin (liver-intestine). | 0.742 |
ctnnb1 | cdh18a | ENSDARP00000139205 | ENSDARP00000089931 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Cadherin 18, type 2a. | 0.643 |
ctnnb1 | ctnnb2 | ENSDARP00000139205 | ENSDARP00000076115 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Catenin, beta 2. | 0.924 |
ctnnb1 | jupa | ENSDARP00000139205 | ENSDARP00000026915 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Junction plakoglobin a. | 0.958 |
ctnnb1 | jupb | ENSDARP00000139205 | ENSDARP00000076517 | Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] | Junction plakoglobin b. | 0.833 |