Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fukFucose kinase. (969 aa)    
Predicted Functional Partners:
fpgt
Fucose-1-phosphate guanylyltransferase.
     
 0.998
hkdc1
Hexokinase domain-containing 1.
     
 0.956
sord
Sorbitol dehydrogenase.
    
  0.948
hsd17b14
Hydroxysteroid (17-beta) dehydrogenase 14.
     
  0.944
khk
Ketohexokinase.
     
  0.944
hk2
Hexokinase 2.
     
 0.917
hk1
Hexokinase 1.
     
 0.899
gmds
GDP-mannose 4,6 dehydratase.
     
 0.836
cog4
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function. Plays a role in the vesicular trafficking between the endoplasmic reticulum and the Golgi apparatus (By similarity); Belongs to the COG4 family.
      
 0.836
galm
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
     
 0.824
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]