Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc1a4Amino acid transporter. (517 aa)    
Predicted Functional Partners:
slc7a5
Solute carrier family 7 member 5.
   
 
 0.889
slc38a9
Sodium-coupled neutral amino acid transporter 9; Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels. Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. SLC38A9 mediates transport of a [...]
      
 0.759
slc3a2a
Solute carrier family 3 member 2a.
   
 
 0.756
slc16a10
Monocarboxylate transporter 10; Sodium-independent transporter that mediates the uptake of aromatic acids; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
      
 0.733
slc3a1
Solute carrier family 3 member 1.
   
 
 0.718
slc7a9
Solute carrier family 7 member 9.
    
 
 0.712
slc6a19b
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
    
 0.703
slc7a1a
Solute carrier family 7 member 1a.
   
 
 0.700
SLC7A1
Solute carrier family 7 member 1.
   
 
 0.699
slc7a6
Y+L amino acid transporter 2; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
    
 
 0.698
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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