Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ppdpfbPancreatic progenitor cell differentiation and proliferation factor B; Probable regulator of exocrine pancreas development. (115 aa)    
Predicted Functional Partners:
map3k15
Mitogen-activated protein kinase kinase kinase 15.
      
 0.687
serinc1
Serine incorporator 1.
   
  
 0.671
ptmaa
Prothymosin alpha-A.
   
  
 0.596
fbxl3a
Novel protein similar to human and mouse F-box and leucine-rich repeat protein 3A (FBXL3A).
      
 0.595
spon1b
Spondin 1b.
      
 0.566
pnoca
Prepronociceptin a.
      
 0.566
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.501
gpr22a
G-protein coupled receptor 22; Orphan G-protein coupled receptor that regulates cilia length and structure in the Kupffer's vesicle leading to the left-right asymmetry development by establishing a directional fluid flow.
      
 0.500
akt1s1
AKT1 substrate 1 (proline-rich).
      
 0.468
dynll2a
Dynein, light chain, LC8-type 2a.
   
  
 0.427
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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