Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cst14a.1Cystatin 14a, tandem duplicate 1; Belongs to the cystatin family. (100 aa)    
Predicted Functional Partners:
tnfsf13b
TNF superfamily member 13b; Belongs to the tumor necrosis factor family.
    
 
 0.785
ctsba
Cathepsin B, a; Belongs to the peptidase C1 family.
   
 0.694
ctsbb
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.694
uqcr10
Ubiquinol-cytochrome c reductase, complex III subunit X.
   
 
 0.612
ctsh
Cathepsin H; Belongs to the peptidase C1 family.
    
 0.584
Ndufa13
Uncharacterized protein.
   
   0.538
ndufa2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
   
   0.535
ndufa5
NADH:ubiquinone oxidoreductase subunit A5.
    
 
 0.533
ndufb7
NADH:ubiquinone oxidoreductase subunit B7.
   
   0.529
ndufb9
NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 9; Belongs to the complex I LYR family.
    
   0.526
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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