Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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paqr7bMembrane progestin receptor alpha-B; Steroid membrane receptor. Signals upon progestin binding, resulting in rapid activation of MAPK and down-regulation of adenylyl cyclase activity. Interacts with steroids with varying degrees of affinity, showing specificity for activation by the maturation-inducing steroid (MIS) 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP). Capable of mediating progestin-induced oocyte maturation. (354 aa)    
Predicted Functional Partners:
appl1
HESX homeobox 1.
    
 0.943
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2.
    
  0.930
pgrmc2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
   
 
 0.821
pgrmc1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
   
 
 0.818
pgr
Progesterone receptor.
    
 
 0.781
paqr6
Progestin and adipoQ receptor family member VI.
   
 
0.764
paqr5a
Membrane progestin receptor gamma-A; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity); Belongs to the ADIPOR family.
  
  
0.755
paqr5b
Membrane progestin receptor gamma-B; Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation (By similarity). Belongs to the ADIPOR family.
     
0.727
pigw
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
      
 0.692
paqr3a
Progestin and adipoQ receptor family member IIIa.
      
 0.687
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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