Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rsrp1Arginine/serine-rich protein 1; Belongs to the RSRP family. (321 aa)    
Predicted Functional Partners:
ap5s1
Adaptor-related protein complex 5 subunit sigma 1.
      
 0.882
psme3ip1
Family with sequence similarity 192 member A.
    
   0.880
tbc1d31
TBC1 domain family, member 31.
      
 0.799
alpk2
Alpha-protein kinase 2; Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (By similarity). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling.
      
 0.730
rhd
Rh blood group, D antigen; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.728
syf2
Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome.
      
 0.728
tmem50a
Transmembrane protein 50A.
      
 0.728
clk4a
CDC-like kinase 4a; Belongs to the protein kinase superfamily.
   
 
 0.704
MYADM
Si:dkeyp-67a8.2.
      
 0.666
TMCC1
Transmembrane and coiled-coil domain family 1.
      
 0.662
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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