Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ZBTB26Si:ch211-236k19.4. (411 aa)    
Predicted Functional Partners:
pbk
Lymphokine-activated killer T-cell-originated protein kinase homolog.
    
  0.491
parpbp
PCNA-interacting partner; Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability; Belongs to the PARI family.
    
 
 0.464
rrp12
Ribosomal RNA-processing 12 homolog.
      
 0.453
rnf2
E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin he [...]
    
 
 0.450
btbd7
BTB (POZ) domain-containing 7.
      
 0.441
ankfy1
Ankyrin repeat and FYVE domain-containing 1.
    
 0.439
skiv2l
SKI2 homolog, superkiller viralicidic activity 2-like.
    
 
 0.437
exd3
Exonuclease 3'-5' domain-containing 3.
    
 
 0.430
ipo9
Importin 9.
      
 0.425
kctd2
Potassium channel tetramerization domain-containing 2.
    
 0.401
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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