Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
traf2aTNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (575 aa)    
Predicted Functional Partners:
tradd
Tumor necrosis factor receptor type 1-associated DEATH domain protein; Adapter molecule for tnfrsf1a that specifically associates with the cytoplasmic domain of activated tnfrsf1a mediating its interaction with fadd.
    
 0.996
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
    
 0.994
birc2
Baculoviral IAP repeat-containing 2.
   
 0.991
fadd
Fas (tnfrsf6)-associated via death domain.
    
 0.990
tnfrsf1b
Tumor necrosis factor receptor superfamily, member 1B.
   
 0.981
ripk1l
Receptor (TNFRSF)-interacting serine-threonine kinase 1,-like.
   
 0.979
LOC100334396
Uncharacterized protein.
    
 0.979
rps27a
Ribosomal protein S27a.
    
  0.976
tab1
TGF-beta-activated kinase 1/MAP3K7-binding protein 1.
   
 0.975
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.974
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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