Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
B8JK25_DANRESi:dkey-256e7.5. (355 aa)    
Predicted Functional Partners:
efhc2
EF-hand domain-containing family member C2.
   
 
 0.974
efhb
EF-hand domain family, member B.
   
 
 0.972
efhc1
EF-hand domain (C-terminal)-containing 1.
   
 
 0.961
spag8
Sperm-associated antigen 8.
   
 
 0.949
cfap52
Cilia and flagella-associated protein 52.
   
 
 0.943
tekt2
Tektin 2 (testicular).
   
 
 0.938
ccdc105
Coiled-coil domain-containing 105.
   
 
 0.912
cfap161
Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly.
   
 
 0.885
fam183a
Family with sequence similarity 183 member A.
    
 
 0.883
fam166c
Family with sequence similarity 166 member C.
    
 
 0.860
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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