uspl1 protein (Danio rerio) - STRING interaction network

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uspl1

SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity). (1014 aa)

Predicted Functional Partners:

desi1a

0.887

ice2

0.862

desi1b

0.859

sumo3b

0.847

sumo2a

0.847

senp5

0.807

ell

0.737

snrnp40

0.734

C18H19orf54

0.728

ints14

0.725

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C18H19orf54	snrnp40	ENSDARP00000057732	ENSDARP00000038728	UPF0692 protein C19orf54 homolog; Belongs to the UPF0692 family.	Small nuclear ribonucleoprotein 40 (U5).	0.430
C18H19orf54	uspl1	ENSDARP00000057732	ENSDARP00000043801	UPF0692 protein C19orf54 homolog; Belongs to the UPF0692 family.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.728
desi1a	senp5	ENSDARP00000048870	ENSDARP00000080136	PPPDE peptidase domain containing 2a.	SUMO-specific peptidase 5.	0.720
desi1a	uspl1	ENSDARP00000048870	ENSDARP00000043801	PPPDE peptidase domain containing 2a.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.887
desi1b	senp5	ENSDARP00000108643	ENSDARP00000080136	PPPDE peptidase domain containing 2b.	SUMO-specific peptidase 5.	0.813
desi1b	sumo2a	ENSDARP00000108643	ENSDARP00000131474	PPPDE peptidase domain containing 2b.	Small ubiquitin-related modifier.	0.424
desi1b	sumo3b	ENSDARP00000108643	ENSDARP00000052255	PPPDE peptidase domain containing 2b.	Small ubiquitin-related modifier.	0.420
desi1b	uspl1	ENSDARP00000108643	ENSDARP00000043801	PPPDE peptidase domain containing 2b.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.859
ell	ice2	ENSDARP00000155550	ENSDARP00000104472	Elongation factor RNA polymerase II.	Interactor of little elongator complex ELL subunit 2.	0.977
ell	ints14	ENSDARP00000155550	ENSDARP00000111847	Elongation factor RNA polymerase II.	Integrator complex subunit 14.	0.500
ell	uspl1	ENSDARP00000155550	ENSDARP00000043801	Elongation factor RNA polymerase II.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.737
ice2	ell	ENSDARP00000104472	ENSDARP00000155550	Interactor of little elongator complex ELL subunit 2.	Elongation factor RNA polymerase II.	0.977
ice2	ints14	ENSDARP00000104472	ENSDARP00000111847	Interactor of little elongator complex ELL subunit 2.	Integrator complex subunit 14.	0.512
ice2	snrnp40	ENSDARP00000104472	ENSDARP00000038728	Interactor of little elongator complex ELL subunit 2.	Small nuclear ribonucleoprotein 40 (U5).	0.593
ice2	uspl1	ENSDARP00000104472	ENSDARP00000043801	Interactor of little elongator complex ELL subunit 2.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.862
ints14	ell	ENSDARP00000111847	ENSDARP00000155550	Integrator complex subunit 14.	Elongation factor RNA polymerase II.	0.500
ints14	ice2	ENSDARP00000111847	ENSDARP00000104472	Integrator complex subunit 14.	Interactor of little elongator complex ELL subunit 2.	0.512
ints14	uspl1	ENSDARP00000111847	ENSDARP00000043801	Integrator complex subunit 14.	SUMO-specific isopeptidase USPL1; SUMO-specific isopeptidase involved in protein desumoylation. Specifically binds SUMO proteins with a higher affinity for sumo2 and sumo3 which it cleaves more efficiently. Also able to process full- length SUMO proteins to their mature forms. Plays a key role in RNA polymerase-II-mediated snRNA transcription in the Cajal bodies (By similarity). Is a component of complexes that can bind to U snRNA genes (By similarity).	0.725
senp5	desi1a	ENSDARP00000080136	ENSDARP00000048870	SUMO-specific peptidase 5.	PPPDE peptidase domain containing 2a.	0.720
senp5	desi1b	ENSDARP00000080136	ENSDARP00000108643	SUMO-specific peptidase 5.	PPPDE peptidase domain containing 2b.	0.813

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