Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
osbpl10bOxysterol-binding protein; Belongs to the OSBP family. (752 aa)    
Predicted Functional Partners:
osbpl9
Oxysterol-binding protein; Belongs to the OSBP family.
   
   0.750
ccdc9
Coiled-coil domain-containing 9.
     
 0.736
dcaf6
Ddb1 and cul4-associated factor 6.
      
 0.718
p4ha1a
Prolyl 4-hydroxylase, alpha polypeptide I a.
      
 0.689
ptprub
Receptor-type tyrosine-protein phosphatase U; Tyrosine-protein phosphatase which dephosphorylates CTNNB1. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. Functions in somitogenesis. Functions as a regulator of the biochemical clock responsible for the segmentation of the presomitic mesoderm; Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
   
  
 0.675
nhsl1b
NHS-like 1b.
      
 0.667
lmtk2
Lemur tyrosine kinase 2.
      
 0.663
atad1b
ATPase family AAA domain-containing protein 1-B; ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner (By similarity).
   
  
 0.607
pcdhb
Protocadherin b.
      
 0.595
smim7
Small integral membrane protein 7.
      
 0.590
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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