Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mpp6bMembrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (539 aa)    
Predicted Functional Partners:
cacnb2b
Voltage-dependent calcium channel beta 2a subunit.
      
 0.736
cacnb2a
Calcium channel, voltage-dependent, beta 2a.
      
 0.736
icn2
Protein S100; Belongs to the S-100 family.
    
 
 0.728
snx19a
Sorting nexin 19a.
      
 0.687
camk2d1
Calcium/calmodulin-dependent protein kinase type II delta 1 chain; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system.
 
  
  0.667
camk2a
Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
 
  
  0.655
dars1
Aspartyl-tRNA synthetase.
  
  
 0.647
vwde
Von Willebrand factor D and EGF domains.
    
 0.599
lin7a
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 
 0.585
lin7b
Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.
    
 
 0.585
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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