Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
agfg1aArfGAP with FG repeats 1a. (556 aa)    
Predicted Functional Partners:
fcho2
F-BAR domain only protein 2; May function in an early step of clathrin-mediated endocytosis.
    
 
 0.882
eps15
Epidermal growth factor receptor pathway substrate 15.
   
 
 0.848
fcho1
F-BAR domain only protein 1.
    
 
 0.797
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.682
maco1a
Macoilin-1; May play a role in the regulation of neuronal activity. Belongs to the macoilin family.
      
 0.662
LOC795051
PDZ domain-containing protein.
      
 0.661
ston2
Stonin 2; Belongs to the Stoned B family.
   
  
 0.606
dab2
DAB adaptor protein 2.
      
 0.594
rnf19a
RBR-type E3 ubiquitin transferase.
   
  
 0.583
ahnak
AHNAK nucleoprotein.
      
 0.577
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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