scn4ab protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

scn4ab

Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles. (1835 aa)

Predicted Functional Partners:

scn1ba

0.959

scn4ba

0.916

scn1bb

0.913

scn3b

0.843

LOC108179162

0.800

R4GEQ7_DANRE

0.800

R4GES4_DANRE

0.800

zgc:173915-2

0.800

LOC100334800

0.800

LOC566119

0.800

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100334800	scn4ab	ENSDARP00000145184	ENSDARP00000094779	Fibrinogen C-terminal domain-containing protein.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.800
LOC108179162	scn4ab	ENSDARP00000126806	ENSDARP00000094779	Si:zfos-2330d3.7.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.800
LOC566119	scn4ab	ENSDARP00000153116	ENSDARP00000094779	Fibrinogen C-terminal domain-containing protein.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.800
R4GEQ7_DANRE	scn4ab	ENSDARP00000126970	ENSDARP00000094779	Si:zfos-2330d3.7.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.800
R4GES4_DANRE	scn4ab	ENSDARP00000126987	ENSDARP00000094779	Si:ch1073-110a20.2.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.800
scn1ba	scn1bb	ENSDARP00000079066	ENSDARP00000135746	Voltage-gated sodium channel beta 1 subunit splice variant D.	Sodium channel, voltage-gated, type I, beta b.	0.907
scn1ba	scn3b	ENSDARP00000079066	ENSDARP00000123929	Voltage-gated sodium channel beta 1 subunit splice variant D.	Sodium channel, voltage-gated, type III, beta.	0.657
scn1ba	scn4ab	ENSDARP00000079066	ENSDARP00000094779	Voltage-gated sodium channel beta 1 subunit splice variant D.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.959
scn1ba	scn4ba	ENSDARP00000079066	ENSDARP00000131247	Voltage-gated sodium channel beta 1 subunit splice variant D.	Voltage-gated sodium channel beta 4 subunit locus 1.	0.976
scn1bb	scn1ba	ENSDARP00000135746	ENSDARP00000079066	Sodium channel, voltage-gated, type I, beta b.	Voltage-gated sodium channel beta 1 subunit splice variant D.	0.907
scn1bb	scn3b	ENSDARP00000135746	ENSDARP00000123929	Sodium channel, voltage-gated, type I, beta b.	Sodium channel, voltage-gated, type III, beta.	0.627
scn1bb	scn4ab	ENSDARP00000135746	ENSDARP00000094779	Sodium channel, voltage-gated, type I, beta b.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.913
scn1bb	scn4ba	ENSDARP00000135746	ENSDARP00000131247	Sodium channel, voltage-gated, type I, beta b.	Voltage-gated sodium channel beta 4 subunit locus 1.	0.950
scn3b	scn1ba	ENSDARP00000123929	ENSDARP00000079066	Sodium channel, voltage-gated, type III, beta.	Voltage-gated sodium channel beta 1 subunit splice variant D.	0.657
scn3b	scn1bb	ENSDARP00000123929	ENSDARP00000135746	Sodium channel, voltage-gated, type III, beta.	Sodium channel, voltage-gated, type I, beta b.	0.627
scn3b	scn4ab	ENSDARP00000123929	ENSDARP00000094779	Sodium channel, voltage-gated, type III, beta.	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	0.843
scn3b	scn4ba	ENSDARP00000123929	ENSDARP00000131247	Sodium channel, voltage-gated, type III, beta.	Voltage-gated sodium channel beta 4 subunit locus 1.	0.834
scn4ab	LOC100334800	ENSDARP00000094779	ENSDARP00000145184	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	Fibrinogen C-terminal domain-containing protein.	0.800
scn4ab	LOC108179162	ENSDARP00000094779	ENSDARP00000126806	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	Si:zfos-2330d3.7.	0.800
scn4ab	LOC566119	ENSDARP00000094779	ENSDARP00000153116	Sodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles.	Fibrinogen C-terminal domain-containing protein.	0.800

page 1 of 2

Server load: medium (42%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About