Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
mmp14bMatrix metallopeptidase 14b (membrane-inserted). (621 aa)    
Predicted Functional Partners:
timp2a
Tissue inhibitor of metalloproteinase 2.
   
 0.992
mmp2
Matrix metalloproteinase 2.
   
0.979
mmp14a
Matrix metallopeptidase 14a (membrane-inserted).
  
 
0.956
furina
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
    
 0.799
dcn
Decorin; May affect the rate of fibrils formation. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
  0.776
rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
      
 0.756
igfbp1a
Insulin-like growth factor-binding protein 1a.
    
 
 0.748
myog
Myogenin.
    
 
 0.742
hbegfa
Heparin-binding EGF-like growth factor a.
   
 0.725
hbegfb
Heparin-binding EGF-like growth factor b.
   
 0.725
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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