| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| abat | acat1 | ENSDARP00000125625 | ENSDARP00000133230 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.461 |
| abat | acat2 | ENSDARP00000125625 | ENSDARP00000018064 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.493 |
| abat | acox1 | ENSDARP00000125625 | ENSDARP00000049225 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.952 |
| abat | acox3 | ENSDARP00000125625 | ENSDARP00000056744 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.947 |
| abat | acss1 | ENSDARP00000125625 | ENSDARP00000044327 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetyl-coenzyme A synthetase. | 0.967 |
| abat | cs | ENSDARP00000125625 | ENSDARP00000135698 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Citrate synthase, mitochondrial. | 0.819 |
| abat | mlycd | ENSDARP00000125625 | ENSDARP00000132011 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Malonyl-CoA decarboxylase. | 0.518 |
| acacb | acat1 | ENSDARP00000083511 | ENSDARP00000133230 | Acetyl-CoA carboxylase beta. | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 0.959 |
| acacb | acat2 | ENSDARP00000083511 | ENSDARP00000018064 | Acetyl-CoA carboxylase beta. | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.947 |
| acacb | acox1 | ENSDARP00000083511 | ENSDARP00000049225 | Acetyl-CoA carboxylase beta. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.567 |
| acacb | acss1 | ENSDARP00000083511 | ENSDARP00000044327 | Acetyl-CoA carboxylase beta. | Acetyl-coenzyme A synthetase. | 0.968 |
| acacb | cs | ENSDARP00000083511 | ENSDARP00000135698 | Acetyl-CoA carboxylase beta. | Citrate synthase, mitochondrial. | 0.958 |
| acacb | hadhb | ENSDARP00000083511 | ENSDARP00000151192 | Acetyl-CoA carboxylase beta. | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. | 0.461 |
| acacb | mlycd | ENSDARP00000083511 | ENSDARP00000132011 | Acetyl-CoA carboxylase beta. | Malonyl-CoA decarboxylase. | 0.960 |
| acacb | suclg2 | ENSDARP00000083511 | ENSDARP00000107576 | Acetyl-CoA carboxylase beta. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.956 |
| acat1 | abat | ENSDARP00000133230 | ENSDARP00000125625 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.461 |
| acat1 | acacb | ENSDARP00000133230 | ENSDARP00000083511 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-CoA carboxylase beta. | 0.959 |
| acat1 | acat2 | ENSDARP00000133230 | ENSDARP00000018064 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. | 0.934 |
| acat1 | acox1 | ENSDARP00000133230 | ENSDARP00000049225 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.972 |
| acat1 | acox3 | ENSDARP00000133230 | ENSDARP00000056744 | Acetyl-CoA acetyltransferase, mitochondrial; This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism. Belongs to the thiolase-l [...] | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.975 |
