Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
klhl4Kelch-like family member 4. (327 aa)    
Predicted Functional Partners:
spata2
Spermatogenesis-associated protein 2; Bridging factor that mediates the recruitment of cyld to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis. Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of cyld.
      
 0.815
rassf9
Ras association domain family member 9.
      
 0.737
sowahd
Sosondowah ankyrin repeat domain family d.
   
 
 0.728
E9QH26_DANRE
Si:ch73-29c22.1.
 
  
   0.726
ankdd1a
Ankyrin repeat and death domain-containing 1A.
    
 
 0.724
zgc:162941
Lysozyme g.
    
 
 0.721
RASSF4
Ras association domain family member 4.
      
 0.720
tmem119b
Transmembrane protein 119b.
      
 0.719
TMEM151A
Transmembrane protein 151A.
      
 0.719
LOC101882069
Transmembrane protein 151A.
      
 0.719
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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