STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gna11bGuanine nucleotide-binding protein (G protein), alpha 11b (Gq class). (359 aa)    
Predicted Functional Partners:
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.936
Plcb2
Phosphoinositide phospholipase C.
    
 0.935
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
   
 0.935
ENSDARP00000148213
PH_14 domain-containing protein.
    
 0.935
htr2cl1
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.
    
 0.930
agtr1a
Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.925
agtr1b
Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.925
htr2b
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled.
    
 0.923
adra1aa
Adrenoceptor alpha 1Aa.
    
 0.922
htr2aa
5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a.
    
 0.922
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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