Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ano5aAnoctamin. (915 aa)    
Predicted Functional Partners:
sorbs2b
Sorbin and SH3 domain-containing 2b.
      
 0.922
ano3
Anoctamin.
    
  0.821
dysf
Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive).
      
 0.777
dnajb6b
DnaJ heat shock protein family (Hsp40) member B6b.
      
 0.685
rxraa
Retinoic acid receptor RXR-alpha-A; Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 to regulate transcription. The high affinity ligand for rxrs is 9-cis retinoic acid. In the absence of ligand, the rar/rxr heterodimer [...]
      
 0.661
ano6
Anoctamin.
     
  0.628
katnbl1
Katanin p80 subunit B-like 1.
      
 0.604
fkrp
Fukutin-related protein.
   
  
 0.601
ccdc58
Coiled-coil domain-containing protein 58; Belongs to the CCDC58 family.
      
 0.599
TIMM21
Si:dkey-118j18.1.
      
 0.560
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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