STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adarb1aAdenosine deaminase RNA-specific B1a. (720 aa)    
Predicted Functional Partners:
rec114
REC114 meiotic recombination protein.
    
 
 0.818
mei4
Meiosis-specific protein MEI4; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Belongs to the MEI4L family.
      
 0.746
sycp2
Synaptonemal complex protein 2.
      
 0.733
hormad1
HORMA domain-containing protein 1; Plays a key role in meiotic progression by ensuring that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search, promoting synaptonemal- complex formation independently and playing key role in the male mid- pachytene checkpoint and the female meiotic prophase checkpoint.
   
  
 0.726
fam207a
Family with sequence similarity 207 member A.
      
 0.720
plcd4a
Phosphoinositide phospholipase C.
      
 0.720
ada
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
  
 0.702
spo11
SPO11 initiator of meiotic double stranded breaks.
      
 0.645
LOC108192159
REC8 meiotic recombination protein a.
   
  
 0.595
mfsd6a
Major facilitator superfamily domain-containing protein 6-A.
 
    
 0.553
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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