Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
letmd1LETM1 domain-containing 1. (362 aa)    
Predicted Functional Partners:
pdxkb
Novel protein similar to vertebrate pyridoxal (Pyridoxine, vitamin B6) kinase (PDXK).
      
 0.769
csad
Cysteine sulfinic acid decarboxylase.
      
 0.720
rassf2a
Ras association domain family member 2a.
      
 0.686
rassf2b
Ras association domain family member 2b.
      
 0.686
ubxn1
UBX domain-containing protein 1; Ubiquitin-binding protein that specifically binds 'Lys-6'- linked polyubiquitin chains. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems (By similarity).
      
 0.682
nova1
NOVA alternative-splicing regulator 1.
      
 0.670
acbd3
Acyl-Coenzyme A-binding domain-containing 3.
      
 0.667
tnfaip1
Tumor necrosis factor, alpha-induced protein 1 (endothelial).
      
 0.665
mycbp
MYC-binding protein.
      
 0.665
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10.
      
 0.649
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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