Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
ftcdFormimidoyltransferase cyclodeaminase. (550 aa)    
Predicted Functional Partners:
AMDHD1
Probable imidazolonepropionase.
  
 
 0.990
shmt2
Serine hydroxymethyltransferase 2 (mitochondrial).
  
 
 0.973
dmgdh
Dimethylglycine dehydrogenase.
  
 
 0.972
shmt1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.972
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.970
sardh
Sarcosine dehydrogenase.
  
 
 0.968
dhfr
Dihydrofolate reductase.
     
 0.966
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.965
mthfd2
Mthfd2 protein.
    
 0.963
mthfd1b
Methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1b.
    
 0.962
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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