Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gria1bGlutamate receptor, ionotropic, AMPA 1b. (917 aa)    
Predicted Functional Partners:
gria2b
Glutamate receptor, ionotropic, AMPA 2b.
   
 0.831
gria2a
Glutamate receptor, ionotropic, AMPA 2a.
   
 0.831
pick1
Protein-interacting with prkca 1.
    
 
 0.629
grin1a
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
   
0.622
cnih1
Cornichon family AMPA receptor auxiliary protein 1.
    
 
 0.611
cacng2a
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 
 0.606
grin1b
Glutamate receptor, ionotropic, N-methyl D-aspartate 1b.
   
0.602
grm1b
Glutamate receptor, metabotropic 1b.
   
  
 0.589
kcnab2b
Potassium voltage-gated channel, shaker-related subfamily, beta member 2 b.
      
 0.586
dlg4
Disks large homolog 4; Plays a role in synapse assembly and function. Plays a role in synaptic plasticity.
   
 
 0.583
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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