| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahr1a | maff | ENSDARP00000017676 | ENSDARP00000044859 | Aryl hydrocarbon receptor 1a. | V-maf musculoaponeurotic fibrosarcoma oncogene homolog f (Avian). | 0.593 |
| ahr1a | nfe2l2a | ENSDARP00000017676 | ENSDARP00000062853 | Aryl hydrocarbon receptor 1a. | Nuclear factor (Erythroid-derived 2)-like 2. | 0.548 |
| ahr1a | nfe2l2b | ENSDARP00000017676 | ENSDARP00000106581 | Aryl hydrocarbon receptor 1a. | Nuclear factor, erythroid 2-like 2b. | 0.631 |
| ahr1a | nqo1 | ENSDARP00000017676 | ENSDARP00000021150 | Aryl hydrocarbon receptor 1a. | NAD(P)H dehydrogenase, quinone 1. | 0.423 |
| bach2b | maff | ENSDARP00000116013 | ENSDARP00000044859 | BTB and CNC homology 1, basic leucine zipper transcription factor 2b. | V-maf musculoaponeurotic fibrosarcoma oncogene homolog f (Avian). | 0.738 |
| bach2b | nfe2l3 | ENSDARP00000116013 | ENSDARP00000150367 | BTB and CNC homology 1, basic leucine zipper transcription factor 2b. | Nuclear factor, erythroid 2-like 3. | 0.400 |
| keap1a | keap1b | ENSDARP00000045762 | ENSDARP00000124228 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | 0.950 |
| keap1a | maff | ENSDARP00000045762 | ENSDARP00000044859 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | V-maf musculoaponeurotic fibrosarcoma oncogene homolog f (Avian). | 0.560 |
| keap1a | nfe2 | ENSDARP00000045762 | ENSDARP00000002745 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2. | 0.752 |
| keap1a | nfe2l2a | ENSDARP00000045762 | ENSDARP00000062853 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor (Erythroid-derived 2)-like 2. | 0.991 |
| keap1a | nfe2l2b | ENSDARP00000045762 | ENSDARP00000106581 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2-like 2b. | 0.944 |
| keap1a | nfe2l3 | ENSDARP00000045762 | ENSDARP00000150367 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2-like 3. | 0.694 |
| keap1a | nqo1 | ENSDARP00000045762 | ENSDARP00000021150 | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | NAD(P)H dehydrogenase, quinone 1. | 0.882 |
| keap1b | keap1a | ENSDARP00000124228 | ENSDARP00000045762 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Kelch-like ECH-associated protein 1A; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | 0.950 |
| keap1b | maff | ENSDARP00000124228 | ENSDARP00000044859 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | V-maf musculoaponeurotic fibrosarcoma oncogene homolog f (Avian). | 0.561 |
| keap1b | nfe2 | ENSDARP00000124228 | ENSDARP00000002745 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2. | 0.808 |
| keap1b | nfe2l2a | ENSDARP00000124228 | ENSDARP00000062853 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor (Erythroid-derived 2)-like 2. | 0.947 |
| keap1b | nfe2l2b | ENSDARP00000124228 | ENSDARP00000106581 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2-like 2b. | 0.965 |
| keap1b | nfe2l3 | ENSDARP00000124228 | ENSDARP00000150367 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | Nuclear factor, erythroid 2-like 3. | 0.720 |
| keap1b | nqo1 | ENSDARP00000124228 | ENSDARP00000021150 | Kelch-like ECH-associated protein 1B; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting nfe2l2/nrf2 for ubiquitination. Keap1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of nfe2l2/nrf2, a transcription factor regulating expression of many cytoprotective genes. In response to oxidative stress, different electrophile metabolites trigger non- enzymatic covalent modifications of highly reactive cystei [...] | NAD(P)H dehydrogenase, quinone 1. | 0.414 |