Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
myo1ebMyosin IEb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1096 aa)    
Predicted Functional Partners:
plcd1b
Phosphoinositide phospholipase C.
   
  
 0.738
ostf1
Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
    
 
 0.731
wnk2
WNK lysine deficient protein kinase 2.
    
 
 0.722
wipf2b
WAS/WASL-interacting protein family, member 2b.
   
 
 0.685
wipf2a
WAS/WASL-interacting protein family, member 2a.
   
 
 0.685
waslb
WASP-like actin nucleation-promoting factor b.
   
 
 0.678
wasa
WASP actin nucleation-promoting factor a.
   
 
 0.678
wasb
WASP actin nucleation-promoting factor b.
   
 
 0.678
wasla
WASP-like actin nucleation-promoting factor a.
   
 
 0.678
smtna
Smoothelin a.
      
 0.664
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.