Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfkbibNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta. (394 aa)    
Predicted Functional Partners:
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.998
nfkbiab
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b.
  
0.994
nfkbiaa
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.
  
0.990
nfkb1
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1.
   
 0.986
rel
V-rel avian reticuloendotheliosis viral oncogene homolog.
    
 0.976
chuk
Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily.
    
 0.974
nfkb2
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100).
  
0.971
ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.969
rela
V-rel avian reticuloendotheliosis viral oncogene homolog A.
    
 0.960
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
   
 0.953
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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