STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fnbp1lFormin-binding protein 1-like. (548 aa)    
Predicted Functional Partners:
cdc42l2
Cell division cycle 42-like 2.
    
 0.811
wasla
WASP-like actin nucleation-promoting factor a.
   
 0.765
cdc42
Cell division cycle 42.
    
 
 0.668
tsen2
TSEN2 tRNA-splicing endonuclease subunit.
   
   0.661
waslb
WASP-like actin nucleation-promoting factor b.
   
 
 0.637
wasa
WASP actin nucleation-promoting factor a.
   
 
 0.624
wasb
WASP actin nucleation-promoting factor b.
   
 
 0.624
itsn2a
Intersectin 2a.
   
 
 0.610
itsn2b
Intersectin 2b.
   
 
 0.610
atg3
Ubiquitin-like-conjugating enzyme ATG3; E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C- terminal Gly of atg8-like proteins (gabarap, gabarapl1, gabarapl2 or map1lc3a). The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8-like proteins from atg3 to phosphatidylethanolamine (PE). This step is required for the membrane association of atg8-like proteins. The formation of the atg8- phosphatidylethanolamine conju [...]
   
 
 0.599
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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