Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mpp4bMembrane protein, palmitoylated 4-like; Belongs to the MAGUK family. (426 aa)    
Predicted Functional Partners:
mpp5a
MAGUK p55 subfamily member 5-A; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis (By similarity). Functions in cellular patterning of the retina.
    
  0.820
mpp5b
Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
    
  0.655
ak9
Adenylate kinase 9.
   
 0.504
camk2d1
Calcium/calmodulin-dependent protein kinase type II delta 1 chain; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system.
 
  
  0.491
camk2a
Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
 
  
  0.482
uso1
USO1 homolog, vesicle docking protein (Yeast).
   
 
 0.461
zgc:174895
Zgc:174895.
  
 
 0.439
aprt
Adenine phosphoribosyltransferase.
  
 
 0.439
camk2d2
Calcium/calmodulin-dependent protein kinase type II delta 2 chain; CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system.
 
  
  0.420
tyms
Thymidylate synthetase.
   
 
 0.406
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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