| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| atad2 | cdk11b | ENSDARP00000098579 | ENSDARP00000138340 | ATPase family AAA domain-containing 2. | Cyclin-dependent kinase 11B. | 0.799 |
| atad2 | ddx43 | ENSDARP00000098579 | ENSDARP00000092253 | ATPase family AAA domain-containing 2. | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | 0.738 |
| atad2 | prdm9 | ENSDARP00000098579 | ENSDARP00000026323 | ATPase family AAA domain-containing 2. | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | 0.700 |
| atad2 | srgap2 | ENSDARP00000098579 | ENSDARP00000045390 | ATPase family AAA domain-containing 2. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.814 |
| cdc42 | robo4 | ENSDARP00000129339 | ENSDARP00000112841 | Cell division cycle 42. | Roundabout, axon guidance receptor, homolog 4 (Drosophila). | 0.414 |
| cdc42 | srgap2 | ENSDARP00000129339 | ENSDARP00000045390 | Cell division cycle 42. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.844 |
| cdc42l2 | srgap2 | ENSDARP00000123487 | ENSDARP00000045390 | Cell division cycle 42-like 2. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.814 |
| cdk11b | atad2 | ENSDARP00000138340 | ENSDARP00000098579 | Cyclin-dependent kinase 11B. | ATPase family AAA domain-containing 2. | 0.799 |
| cdk11b | ddx43 | ENSDARP00000138340 | ENSDARP00000092253 | Cyclin-dependent kinase 11B. | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | 0.747 |
| cdk11b | prdm9 | ENSDARP00000138340 | ENSDARP00000026323 | Cyclin-dependent kinase 11B. | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | 0.716 |
| cdk11b | srgap2 | ENSDARP00000138340 | ENSDARP00000045390 | Cyclin-dependent kinase 11B. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.827 |
| ddx43 | atad2 | ENSDARP00000092253 | ENSDARP00000098579 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | ATPase family AAA domain-containing 2. | 0.738 |
| ddx43 | cdk11b | ENSDARP00000092253 | ENSDARP00000138340 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | Cyclin-dependent kinase 11B. | 0.747 |
| ddx43 | prdm9 | ENSDARP00000092253 | ENSDARP00000026323 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | 0.655 |
| ddx43 | srgap2 | ENSDARP00000092253 | ENSDARP00000045390 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.832 |
| fam131c | srgap2 | ENSDARP00000134944 | ENSDARP00000045390 | Family with sequence similarity 131 member C. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.781 |
| prdm9 | atad2 | ENSDARP00000026323 | ENSDARP00000098579 | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | ATPase family AAA domain-containing 2. | 0.700 |
| prdm9 | cdk11b | ENSDARP00000026323 | ENSDARP00000138340 | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | Cyclin-dependent kinase 11B. | 0.716 |
| prdm9 | ddx43 | ENSDARP00000026323 | ENSDARP00000092253 | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family. | 0.655 |
| prdm9 | srgap2 | ENSDARP00000026323 | ENSDARP00000045390 | Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] | 0.745 |
