STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shisa2aShisa family member 2a. (258 aa)    
Predicted Functional Partners:
vopp1
VOPP1 WW domain-binding protein.
      
 0.743
trabd2a
Metalloprotease TIKI1; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation (By similarity).
      
 0.740
cyyr1
Cysteine and tyrosine-rich protein 1.
      
 0.691
wbp1
WW domain-binding protein 1.
      
 0.663
tmem91
Transmembrane protein 91.
      
 0.646
znfl1h
Zinc finger-like gene 1h.
      
 0.645
LOC792447
Gsg1-like 2a.
      
 0.644
syndig1l
Synapse differentiation-inducing gene protein 1-like.
      
 0.563
cnih2
Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs); Belongs to the cornichon family.
      
 0.562
cnih1
Cornichon family AMPA receptor auxiliary protein 1.
      
 0.552
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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