Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
F1Q4X3_DANRESi:dkey-222n6.2; Belongs to the intermediate filament family. (382 aa)    
Predicted Functional Partners:
krt222
Keratin 222; Belongs to the intermediate filament family.
   
 0.691
ube2v1
Ubiquitin-conjugating enzyme E2 variant 1.
   
 
 0.656
F1QZM3_DANRE
Si:ch211-194p6.10.
      
 0.595
zgc:153219
Zgc:153219.
      
 0.595
ENSDARP00000142641
Si:ch211-194p6.12.
      
 0.595
itln4
Si:dkey-182o15.5.
      
 0.595
bag3
BCL2-associated athanogene 3.
    
   0.582
itln3
Intelectin 3.
      
 0.560
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.514
im:7150573
Intelectin 2.
      
 0.504
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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