node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
elk4 | lef1 | ENSDARP00000093624 | ENSDARP00000114249 | ETS transcription factor ELK4. | Lymphocyte enhancer binding factor 1 Lef1. | 0.935 |
elk4 | tcf7 | ENSDARP00000093624 | ENSDARP00000128252 | ETS transcription factor ELK4. | Transcription factor 7. | 0.717 |
elk4 | tcf7l1a | ENSDARP00000093624 | ENSDARP00000090035 | ETS transcription factor ELK4. | Transcription factor 7-like 1-A; Participates in the Wnt signaling pathway. Probably binds to DNA and acts as a repressor in the absence of ctnnb1, and possibly as an activator in its presence. Required early in development for dorsal specific gene activation and during gastrulation for repression of dorsal-specific genes in the marginal zone. Required for head formation and forebrain specification. Regulates anterior-posterior patterning in the neuroectoderm by repressing posterior neural fates. Belongs to the TCF/LEF family. | 0.646 |
elk4 | tcf7l2 | ENSDARP00000093624 | ENSDARP00000009531 | ETS transcription factor ELK4. | Transcription factor 7-like 2 (T-cell specific, HMG-box). | 0.741 |
elk4 | tle3a | ENSDARP00000093624 | ENSDARP00000045678 | ETS transcription factor ELK4. | Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family. | 0.884 |
hdac1 | lef1 | ENSDARP00000051798 | ENSDARP00000114249 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Lymphocyte enhancer binding factor 1 Lef1. | 0.855 |
hdac1 | rbpja | ENSDARP00000051798 | ENSDARP00000026585 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Recombination signal-binding protein for immunoglobulin kappa J region a. | 0.945 |
hdac1 | rbpjb | ENSDARP00000051798 | ENSDARP00000087012 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Recombination signal-binding protein for immunoglobulin kappa J region b. | 0.933 |
hdac1 | rbpjl | ENSDARP00000051798 | ENSDARP00000128811 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Recombination signal-binding protein for immunoglobulin kappa J region-like. | 0.933 |
hdac1 | tcf7 | ENSDARP00000051798 | ENSDARP00000128252 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Transcription factor 7. | 0.667 |
hdac1 | tcf7l1a | ENSDARP00000051798 | ENSDARP00000090035 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Transcription factor 7-like 1-A; Participates in the Wnt signaling pathway. Probably binds to DNA and acts as a repressor in the absence of ctnnb1, and possibly as an activator in its presence. Required early in development for dorsal specific gene activation and during gastrulation for repression of dorsal-specific genes in the marginal zone. Required for head formation and forebrain specification. Regulates anterior-posterior patterning in the neuroectoderm by repressing posterior neural fates. Belongs to the TCF/LEF family. | 0.605 |
hdac1 | tcf7l2 | ENSDARP00000051798 | ENSDARP00000009531 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Transcription factor 7-like 2 (T-cell specific, HMG-box). | 0.794 |
hdac1 | tle3a | ENSDARP00000051798 | ENSDARP00000045678 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family. | 0.924 |
hdac1 | znf703 | ENSDARP00000051798 | ENSDARP00000051552 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Zinc finger protein 703; Transcriptional corepressor which does not bind directly to DNA and may regulate transcription through recruitment of histone deacetylases to gene promoters. Required for segmental gene expression during hindbrain development. May regulate cell adhesion, migration and proliferation. | 0.504 |
lef1 | elk4 | ENSDARP00000114249 | ENSDARP00000093624 | Lymphocyte enhancer binding factor 1 Lef1. | ETS transcription factor ELK4. | 0.935 |
lef1 | hdac1 | ENSDARP00000114249 | ENSDARP00000051798 | Lymphocyte enhancer binding factor 1 Lef1. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.855 |
lef1 | tcf7 | ENSDARP00000114249 | ENSDARP00000128252 | Lymphocyte enhancer binding factor 1 Lef1. | Transcription factor 7. | 0.751 |
lef1 | tcf7l1a | ENSDARP00000114249 | ENSDARP00000090035 | Lymphocyte enhancer binding factor 1 Lef1. | Transcription factor 7-like 1-A; Participates in the Wnt signaling pathway. Probably binds to DNA and acts as a repressor in the absence of ctnnb1, and possibly as an activator in its presence. Required early in development for dorsal specific gene activation and during gastrulation for repression of dorsal-specific genes in the marginal zone. Required for head formation and forebrain specification. Regulates anterior-posterior patterning in the neuroectoderm by repressing posterior neural fates. Belongs to the TCF/LEF family. | 0.649 |
lef1 | tcf7l2 | ENSDARP00000114249 | ENSDARP00000009531 | Lymphocyte enhancer binding factor 1 Lef1. | Transcription factor 7-like 2 (T-cell specific, HMG-box). | 0.649 |
lef1 | tle3a | ENSDARP00000114249 | ENSDARP00000045678 | Lymphocyte enhancer binding factor 1 Lef1. | Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family. | 0.986 |