Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
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[Homology]
Score
rrp36Ribosomal RNA-processing 36. (320 aa)    
Predicted Functional Partners:
abt1
Activator of basal transcription 1.
   
 
 0.994
heatr1
HEAT repeat-containing protein 1; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. Required for cell survival in the CNS through its role in rRNA synthesis and processing.
   
 0.991
utp20
UTP20 small subunit processome component.
   
 0.974
bysl
Bystin-like.
   
 
 0.963
utp3
UTP3 small subunit processome component.
   
 
 0.962
utp6
UTP6 small subunit processome component.
   
 0.962
utp25
Digestive organ expansion factor; Regulates the p53 pathway to control the expansion growth of digestive organs. Required for the expansion growth of intestine, liver and exocrine pancreas, but not endocrine pancreas. May not play a major role during the early stage of endodermal organogenesis.
   
 
 0.957
ddx10
RNA helicase.
   
 
 0.956
nop9
Uncharacterized protein.
   
 
 0.954
rrp9
Ribosomal RNA-processing 9, U3 small nucleolar RNA-binding protein.
   
 
 0.954
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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