STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TXNThioredoxin; Belongs to the thioredoxin family. (108 aa)    
Predicted Functional Partners:
txnipa
Thioredoxin-interacting protein a.
   
 0.999
txnipb
Thioredoxin-interacting protein b.
    
 0.994
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.990
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
 0.987
txnrd3
Thioredoxin reductase 3.
  
 0.987
txn2
Thioredoxin 2.
  
0.975
prdx2
Peroxiredoxin 2.
  
 0.946
prdx1
Peroxiredoxin 1.
  
 0.936
msra
Methionine sulfoxide reductase A.
  
 0.917
gsr
Glutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.912
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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