Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prf1.5Perforin 1.5. (517 aa)    
Predicted Functional Partners:
prf1.2
Perforin 1.2.
  
  
0.671
prf1.7
Perforin 1.7.
     
  0.614
prf1.8
Perforin 1.7.
     
  0.614
prf1.1
Perforin 1.1.
  
  
0.588
prf1.9
Perforin 1.9.
     
  0.519
rps11
Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family.
      
 0.511
hepacam2
HEPACAM family member 2.
  
     0.409
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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