Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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vrk1Serine/threonine-protein kinase VRK1; Serine/threonine kinase involved in Golgi disassembly during the cell cycle; Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily. (425 aa)    
Predicted Functional Partners:
ankle2
Ankyrin repeat and LEM domain-containing 2.
   
 0.977
Q1L957_DANRE
Si:dkey-211g8.4.
    
 
 0.923
banf1
Barrier-to-autointegration factor; Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non- specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity).
   
 
 0.910
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression.
    
 
 0.799
tsen54
TSEN54 tRNA-splicing endonuclease subunit.
      
 0.726
coil
Coilin p80.
   
 0.693
uts2r2
Urotensin-2 receptor 2.
      
 0.692
sap130a
Sin3A-associated protein a.
      
 0.680
exosc3
Exosome component 3.
   
  
 0.669
wu:fc33b09
Exosome component 3.
   
  
 0.669
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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