Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc4a1apSolute carrier family 4 member 1 adaptor protein. (768 aa)    
Predicted Functional Partners:
zrsr2
Zinc finger (CCCH type), RNA-binding motif and serine/arginine-rich 2.
   
   0.936
snrpa1
Small nuclear ribonucleoprotein polypeptide A.
    
   0.927
phf5a
PHD finger protein 5A.
    
 
 0.797
ppp4r2a
Serine/threonine-protein phosphatase 4 regulatory subunit 2-A; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4C); Belongs to the PPP4R2 family.
   
   0.770
ppp4r2b
Serine/threonine-protein phosphatase 4 regulatory subunit 2-B; Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4); Belongs to the PPP4R2 family.
   
   0.770
osgep
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity; Belongs to the KAE1 / TsaD family.
      
 0.749
snrpf
Small nuclear ribonucleoprotein polypeptide F.
    
   0.748
dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8.
    
   0.746
prpf38a
Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome.
   
  
 0.625
exosc9
Exosome complex component RRP45; Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cyto [...]
    
   0.611
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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