Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
wnt2bbProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa)    
Predicted Functional Partners:
fzd2
Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.942
wif1
Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
    
 0.933
fzd5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.933
sfrp5
Secreted frizzled-related protein 5.
    
 0.933
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.932
fzd1
Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.
  
 
 0.929
porcn
Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.
    
 0.926
frzb
Frizzled-related protein.
    
 0.925
porcnl
Porcupine O-acyltransferase-like; Belongs to the membrane-bound acyltransferase family.
    
 0.922
fzd6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.919
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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