Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
capn1aCalpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (704 aa)    
Predicted Functional Partners:
bida
BH3-interacting domain death agonist.
     
  0.944
cast
Calpastatin.
   
 0.938
zgc:153993
Zgc:153993 protein.
   
 
 0.927
E9QFN0_DANRE
Si:dkeyp-50d11.2; Belongs to the peptidase C2 family.
  
 
0.850
zgc:55262
Zgc:55262; Belongs to the peptidase C2 family.
  
  
 
0.827
baxa
BCL2-associated X, apoptosis regulator a.
   
 
 0.792
capns1a
Calpain, small subunit 1 a.
   
0.766
LOC100004321
BCL2-associated X, apoptosis regulator a.
   
 
 0.735
baxb
BCL2-associated X, apoptosis regulator b.
     
 0.728
LOC100534669
Uncharacterized protein.
     
 0.728
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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