Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tcerg1bUncharacterized protein. (992 aa)    
Predicted Functional Partners:
rbm22
Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity). Required for normal early embryogenesis.
   
 
 0.896
ddx46
Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation; Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
   
 
 0.893
mfap1
Microfibril-associated protein 1.
   
 
 0.838
sf3b4
Splicing factor 3b, subunit 4.
    
 
 0.826
cwc15
Protein CWC15 homolog; Involved in pre-mRNA splicing as component of the spliceosome.
   
 
 0.823
prpf38a
Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome.
   
 
 0.823
sf3b1
Splicing factor 3b, subunit 1.
   
 
 0.823
sf3a3
Splicing factor 3a, subunit 3.
   
 
 0.822
bud13
BUD13 homolog.
    
 
 0.805
snw1
SNW domain-containing 1.
   
 
 0.791
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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