STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mfsd2aaSodium-dependent lysophosphatidylcholine symporter 1-A; Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega-3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and [...] (532 aa)    
Predicted Functional Partners:
ZNF335
Si:ch211-269m15.3.
      
 0.689
slc2a1a
Facilitated glucose transporter 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
     
 0.662
tyms
Thymidylate synthetase.
  
 
  0.607
mfsd11
Major facilitator superfamily domain-containing 11.
      
 0.605
tk1
Thymidine kinase.
   
 
  0.597
lsr
Lipolysis-stimulated lipoprotein receptor.
      
 0.590
mfsd12a
Major facilitator superfamily domain-containing 12a.
      
 0.568
mfsd13a
Major facilitator superfamily domain-containing 13A.
      
 0.567
ankle2
Ankyrin repeat and LEM domain-containing 2.
      
 0.567
mfsd9
Major facilitator superfamily domain-containing 9.
      
 0.563
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.