Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lnx2aLigand of numb-protein X 2a. (737 aa)    
Predicted Functional Partners:
numb
NUMB endocytic adaptor protein.
   
 
 0.881
numbl
NUMB-like endocytic adaptor protein.
   
 
 0.880
suox
Sulfite oxidase.
     
  0.872
klhl11
Kelch-like family member 11.
    
 
 0.765
pdzd4
PDZ domain-containing protein.
      
 0.735
tomm34
Translocase of outer mitochondrial membrane 34.
    
 0.690
dharma
Dharma.
      
 0.683
erc2
ELKS/RAB6-interacting/CAST family member 2.
    
 
 0.623
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 
 0.619
amot
Angiomotin.
    
 0.618
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.