Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rhouaRas homolog gene family, member Ua. (254 aa)    
Predicted Functional Partners:
pak4
Non-specific serine/threonine protein kinase.
   
 0.852
pak2a
Non-specific serine/threonine protein kinase.
    
 0.842
pak1
Non-specific serine/threonine protein kinase.
    
 0.752
nck2b
Cytoplasmic protein.
    
 0.747
nck2a
Cytoplasmic protein.
    
 0.747
nck1b
Cytoplasmic protein.
    
 0.747
pard6a
Par-6 family cell polarity regulator alpha.
    
 0.717
ptk2ba
Protein tyrosine kinase 2 beta, a; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.717
git1
G protein-coupled receptor kinase-interacting ArfGAP 1.
    
 0.709
iqgap1
IQ motif-containing GTPase-activating protein 1.
   
 0.701
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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