Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
zar1lZygote arrest 1-like. (312 aa)    
Predicted Functional Partners:
efcab2
EF-hand calcium-binding domain 2.
      
 0.815
zp3f.1
Zona pellucida glycoprotein 3f, tandem duplicate 1.
   
  
 0.804
zp3d.2
Zona pellucida glycoprotein 3d tandem duplicate 2.
   
  
 0.803
zp2l2
Zona pellucida glycoprotein 2,-like 2.
   
  
 0.798
morn3
MORN repeat-containing 3.
      
 0.774
hmbox1a
Homeobox-containing 1a.
    
   0.773
march11
Membrane-associated ring finger (C3HC4) 11.
      
 0.737
zp2.2
Zona pellucida glycoprotein 2, tandem duplicate 2.
   
  
 0.707
spata18
Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...]
      
 0.670
ropn1l
Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family.
      
 0.662
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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