node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSDARP00000135683 | clptm1 | ENSDARP00000135683 | ENSDARP00000046647 | Uncharacterized protein. | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | 0.699 |
ENSDARP00000152227 | clptm1 | ENSDARP00000152227 | ENSDARP00000046647 | HORMA domain-containing protein. | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | 0.479 |
ENSDARP00000152227 | ddx11 | ENSDARP00000152227 | ENSDARP00000025514 | HORMA domain-containing protein. | ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal RNA synthesis. Plays a role in DNA double-strand break (DSB) repair at the DNA replication fork during DNA replication recovery from DNA damage. Plays a role in the regulation of sister chromatid cohesion and mitotic chromosome segregation. Stimulates 5'-single-stranded DNA flap endonuclease activity of FEN1 in an ATP- and helicase-independent mann [...] | 0.639 |
ENSDARP00000152227 | mad1l1 | ENSDARP00000152227 | ENSDARP00000123048 | HORMA domain-containing protein. | Mitotic arrest deficient-like protein 1. | 0.935 |
clptm1 | ENSDARP00000135683 | ENSDARP00000046647 | ENSDARP00000135683 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Uncharacterized protein. | 0.699 |
clptm1 | ENSDARP00000152227 | ENSDARP00000046647 | ENSDARP00000152227 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | HORMA domain-containing protein. | 0.479 |
clptm1 | ddost | ENSDARP00000046647 | ENSDARP00000105892 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | 0.423 |
clptm1 | ddx11 | ENSDARP00000046647 | ENSDARP00000025514 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal RNA synthesis. Plays a role in DNA double-strand break (DSB) repair at the DNA replication fork during DNA replication recovery from DNA damage. Plays a role in the regulation of sister chromatid cohesion and mitotic chromosome segregation. Stimulates 5'-single-stranded DNA flap endonuclease activity of FEN1 in an ATP- and helicase-independent mann [...] | 0.417 |
clptm1 | hacd3 | ENSDARP00000046647 | ENSDARP00000016888 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.434 |
clptm1 | mad1l1 | ENSDARP00000046647 | ENSDARP00000123048 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Mitotic arrest deficient-like protein 1. | 0.531 |
clptm1 | mad2l1 | ENSDARP00000046647 | ENSDARP00000003616 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | MAD2 mitotic arrest deficient-like 1 (yeast). | 0.479 |
clptm1 | ncln | ENSDARP00000046647 | ENSDARP00000076240 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Nicalin-1; Antagonizes Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Ectopic expression results in cyclopia, due to a defect in mesendoderm patterning. Belongs to the nicastrin family. | 0.493 |
clptm1 | smpd4 | ENSDARP00000046647 | ENSDARP00000107263 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. | 0.465 |
clptm1 | zgc:172182 | ENSDARP00000046647 | ENSDARP00000058247 | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | Coiled-coil domain-containing protein 89; Belongs to the CCDC89 family. | 0.730 |
ddost | clptm1 | ENSDARP00000105892 | ENSDARP00000046647 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | 0.423 |
ddost | hacd3 | ENSDARP00000105892 | ENSDARP00000016888 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.502 |
ddost | ncln | ENSDARP00000105892 | ENSDARP00000076240 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Nicalin-1; Antagonizes Nodal signaling and subsequent organization of axial structures during mesodermal patterning. Ectopic expression results in cyclopia, due to a defect in mesendoderm patterning. Belongs to the nicastrin family. | 0.594 |
ddost | smpd4 | ENSDARP00000105892 | ENSDARP00000107263 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. | 0.570 |
ddx11 | ENSDARP00000152227 | ENSDARP00000025514 | ENSDARP00000152227 | ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal RNA synthesis. Plays a role in DNA double-strand break (DSB) repair at the DNA replication fork during DNA replication recovery from DNA damage. Plays a role in the regulation of sister chromatid cohesion and mitotic chromosome segregation. Stimulates 5'-single-stranded DNA flap endonuclease activity of FEN1 in an ATP- and helicase-independent mann [...] | HORMA domain-containing protein. | 0.639 |
ddx11 | clptm1 | ENSDARP00000025514 | ENSDARP00000046647 | ATP-dependent DNA helicase DDX11; DNA-dependent ATPase and ATP-dependent DNA helicase that participates in various functions in genomic stability, including DNA replication, DNA repair and heterochromatin organization as well as in ribosomal RNA synthesis. Plays a role in DNA double-strand break (DSB) repair at the DNA replication fork during DNA replication recovery from DNA damage. Plays a role in the regulation of sister chromatid cohesion and mitotic chromosome segregation. Stimulates 5'-single-stranded DNA flap endonuclease activity of FEN1 in an ATP- and helicase-independent mann [...] | Cleft lip and palate transmembrane protein 1 homolog; May play a role in T-cell development; Belongs to the CLPTM1 family. | 0.417 |